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Apolipoprotein epsilon 3 alleles are associated with indicators of neuronal resilience

BACKGROUND: Epilepsy is associated with precocious development of Alzheimer-type neuropathological changes, including appearance of senile plaques, neuronal loss and glial activation. As inheritance of APOE ε4 allele(s) is reported to favor this outcome, we sought to investigate neuronal and glial r...

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Detalles Bibliográficos
Autores principales: Aboud, Orwa, Mrak, Robert E, Boop, Frederick, Griffin, Sue T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352297/
https://www.ncbi.nlm.nih.gov/pubmed/22502727
http://dx.doi.org/10.1186/1741-7015-10-35