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Exploring the origin and degree of genetic isolation of Anopheles gambiae from the islands of São Tomé and Príncipe, potential sites for testing transgenic-based vector control
The evolutionary processes at play between island and mainland populations of the malaria mosquito vector Anopheles gambiae sensu stricto are of great interest as islands may be suitable sites for preliminary application of transgenic-based vector control strategies. São Tomé and Príncipe, located o...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352388/ https://www.ncbi.nlm.nih.gov/pubmed/25567803 http://dx.doi.org/10.1111/j.1752-4571.2008.00048.x |
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author | Marshall, Jonathon C Pinto, João Charlwood, Jacques Derek Gentile, Gabriele Santolamazza, Federica Simard, Frèdèric Della Torre, Alessandra Donnelly, Martin J Caccone, Adalgisa |
author_facet | Marshall, Jonathon C Pinto, João Charlwood, Jacques Derek Gentile, Gabriele Santolamazza, Federica Simard, Frèdèric Della Torre, Alessandra Donnelly, Martin J Caccone, Adalgisa |
author_sort | Marshall, Jonathon C |
collection | PubMed |
description | The evolutionary processes at play between island and mainland populations of the malaria mosquito vector Anopheles gambiae sensu stricto are of great interest as islands may be suitable sites for preliminary application of transgenic-based vector control strategies. São Tomé and Príncipe, located off the West African coast, have received such attention in recent years. This study investigates the degree of isolation of An. gambiae s.s. populations between these islands and the mainland based on mitochondrial and ribosomal DNA molecular data. We identify possible continental localities from which these island populations derived. For these purposes, we used F(ST) values, haplotype networks, and nested clade analysis to estimate migration rates and patterns. Haplotypes from both markers are geographically widespread across the African continent. Results indicate that the populations from São Tomé and Príncipe are relatively isolated from continental African populations, suggesting they are promising sites for test releases of transgenic individuals. These island populations are possibly derived from two separate continental migrations. This result is discussed in the context of the history of the African slave trade with respect to São Tomé and Príncipe. |
format | Online Article Text |
id | pubmed-3352388 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Blackwell Publishing Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-33523882012-05-24 Exploring the origin and degree of genetic isolation of Anopheles gambiae from the islands of São Tomé and Príncipe, potential sites for testing transgenic-based vector control Marshall, Jonathon C Pinto, João Charlwood, Jacques Derek Gentile, Gabriele Santolamazza, Federica Simard, Frèdèric Della Torre, Alessandra Donnelly, Martin J Caccone, Adalgisa Evol Appl Original Articles The evolutionary processes at play between island and mainland populations of the malaria mosquito vector Anopheles gambiae sensu stricto are of great interest as islands may be suitable sites for preliminary application of transgenic-based vector control strategies. São Tomé and Príncipe, located off the West African coast, have received such attention in recent years. This study investigates the degree of isolation of An. gambiae s.s. populations between these islands and the mainland based on mitochondrial and ribosomal DNA molecular data. We identify possible continental localities from which these island populations derived. For these purposes, we used F(ST) values, haplotype networks, and nested clade analysis to estimate migration rates and patterns. Haplotypes from both markers are geographically widespread across the African continent. Results indicate that the populations from São Tomé and Príncipe are relatively isolated from continental African populations, suggesting they are promising sites for test releases of transgenic individuals. These island populations are possibly derived from two separate continental migrations. This result is discussed in the context of the history of the African slave trade with respect to São Tomé and Príncipe. Blackwell Publishing Ltd 2008-11 2008-10-10 /pmc/articles/PMC3352388/ /pubmed/25567803 http://dx.doi.org/10.1111/j.1752-4571.2008.00048.x Text en © 2008 The Authors. Journal compilation © 2008 Blackwell Publishing Ltd |
spellingShingle | Original Articles Marshall, Jonathon C Pinto, João Charlwood, Jacques Derek Gentile, Gabriele Santolamazza, Federica Simard, Frèdèric Della Torre, Alessandra Donnelly, Martin J Caccone, Adalgisa Exploring the origin and degree of genetic isolation of Anopheles gambiae from the islands of São Tomé and Príncipe, potential sites for testing transgenic-based vector control |
title | Exploring the origin and degree of genetic isolation of Anopheles gambiae from the islands of São Tomé and Príncipe, potential sites for testing transgenic-based vector control |
title_full | Exploring the origin and degree of genetic isolation of Anopheles gambiae from the islands of São Tomé and Príncipe, potential sites for testing transgenic-based vector control |
title_fullStr | Exploring the origin and degree of genetic isolation of Anopheles gambiae from the islands of São Tomé and Príncipe, potential sites for testing transgenic-based vector control |
title_full_unstemmed | Exploring the origin and degree of genetic isolation of Anopheles gambiae from the islands of São Tomé and Príncipe, potential sites for testing transgenic-based vector control |
title_short | Exploring the origin and degree of genetic isolation of Anopheles gambiae from the islands of São Tomé and Príncipe, potential sites for testing transgenic-based vector control |
title_sort | exploring the origin and degree of genetic isolation of anopheles gambiae from the islands of são tomé and príncipe, potential sites for testing transgenic-based vector control |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352388/ https://www.ncbi.nlm.nih.gov/pubmed/25567803 http://dx.doi.org/10.1111/j.1752-4571.2008.00048.x |
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