Cargando…
Rapid selection against inbreeding in a wild population of a rare frog
Populations that are small and isolated can be threatened through loss of fitness due to inbreeding. Nevertheless, an increased frequency of recessive homozygotes could increase the efficiency of selection against deleterious mutants, thus reducing inbreeding depression. In wild populations, observa...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352519/ https://www.ncbi.nlm.nih.gov/pubmed/25567951 http://dx.doi.org/10.1111/j.1752-4571.2010.00130.x |
_version_ | 1782232926786682880 |
---|---|
author | Ficetola, Gentile Francesco Garner, Trenton W J Wang, Jinliang De Bernardi, Fiorenza |
author_facet | Ficetola, Gentile Francesco Garner, Trenton W J Wang, Jinliang De Bernardi, Fiorenza |
author_sort | Ficetola, Gentile Francesco |
collection | PubMed |
description | Populations that are small and isolated can be threatened through loss of fitness due to inbreeding. Nevertheless, an increased frequency of recessive homozygotes could increase the efficiency of selection against deleterious mutants, thus reducing inbreeding depression. In wild populations, observations of evolutionary changes determined by selection against inbreeding are few. We used microsatellite DNA markers to compare the genetic features of tadpoles immediately after hatch with those of metamorphosing froglets belonging to the same cohort in a small, isolated population of the threatened frog Rana latastei. Within a generation, the inbreeding coefficient (F(IS)) decreased: at hatch, F(IS) was significantly >0, whereas F(IS) was <0 after metamorphosis. Furthermore, heterozygosity increased and allelic frequencies changed over time, resulting in the loss of genotypes at metamorphosis that were present in hatchlings. One microsatellite locus exhibited atypically large F(ST) values, suggesting it might be linked to a locus under selection. These results support the hypothesis that strong selection against the most inbred genotypes occurred among early life-history stages in our population. Selective forces can promote changes that can affect population dynamics and should be considered in conservation planning. |
format | Online Article Text |
id | pubmed-3352519 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Blackwell Publishing Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-33525192012-05-24 Rapid selection against inbreeding in a wild population of a rare frog Ficetola, Gentile Francesco Garner, Trenton W J Wang, Jinliang De Bernardi, Fiorenza Evol Appl Original Articles Populations that are small and isolated can be threatened through loss of fitness due to inbreeding. Nevertheless, an increased frequency of recessive homozygotes could increase the efficiency of selection against deleterious mutants, thus reducing inbreeding depression. In wild populations, observations of evolutionary changes determined by selection against inbreeding are few. We used microsatellite DNA markers to compare the genetic features of tadpoles immediately after hatch with those of metamorphosing froglets belonging to the same cohort in a small, isolated population of the threatened frog Rana latastei. Within a generation, the inbreeding coefficient (F(IS)) decreased: at hatch, F(IS) was significantly >0, whereas F(IS) was <0 after metamorphosis. Furthermore, heterozygosity increased and allelic frequencies changed over time, resulting in the loss of genotypes at metamorphosis that were present in hatchlings. One microsatellite locus exhibited atypically large F(ST) values, suggesting it might be linked to a locus under selection. These results support the hypothesis that strong selection against the most inbred genotypes occurred among early life-history stages in our population. Selective forces can promote changes that can affect population dynamics and should be considered in conservation planning. Blackwell Publishing Ltd 2011-01 2010-05-10 /pmc/articles/PMC3352519/ /pubmed/25567951 http://dx.doi.org/10.1111/j.1752-4571.2010.00130.x Text en © 2010 Blackwell Publishing Ltd |
spellingShingle | Original Articles Ficetola, Gentile Francesco Garner, Trenton W J Wang, Jinliang De Bernardi, Fiorenza Rapid selection against inbreeding in a wild population of a rare frog |
title | Rapid selection against inbreeding in a wild population of a rare frog |
title_full | Rapid selection against inbreeding in a wild population of a rare frog |
title_fullStr | Rapid selection against inbreeding in a wild population of a rare frog |
title_full_unstemmed | Rapid selection against inbreeding in a wild population of a rare frog |
title_short | Rapid selection against inbreeding in a wild population of a rare frog |
title_sort | rapid selection against inbreeding in a wild population of a rare frog |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352519/ https://www.ncbi.nlm.nih.gov/pubmed/25567951 http://dx.doi.org/10.1111/j.1752-4571.2010.00130.x |
work_keys_str_mv | AT ficetolagentilefrancesco rapidselectionagainstinbreedinginawildpopulationofararefrog AT garnertrentonwj rapidselectionagainstinbreedinginawildpopulationofararefrog AT wangjinliang rapidselectionagainstinbreedinginawildpopulationofararefrog AT debernardifiorenza rapidselectionagainstinbreedinginawildpopulationofararefrog |