A fatal case of AIDS-defining meningoencephalitis by C. Neoformans, sensitive to antifungal therapy

Cryptococcus neoformans is the most common cause of life threatening meningoencephalitis in HIV-infected patients. Diagnosis is based on tests for cryptoccocal antigen in serum and cerebrospinal fluid, and on culture of the organism. We present a case of AIDS-related cryptococcal meningoencephalitis...

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Autores principales: Mohammad-Khani, S, Otremba, B, Klein, R, Capelle, HH, Logemann, F, Bange, FC, Schmidt, RE, Stoll, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352659/
https://www.ncbi.nlm.nih.gov/pubmed/21159575
http://dx.doi.org/10.1186/2047-783X-15-11-504
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author Mohammad-Khani, S
Otremba, B
Klein, R
Capelle, HH
Logemann, F
Bange, FC
Schmidt, RE
Stoll, M
author_facet Mohammad-Khani, S
Otremba, B
Klein, R
Capelle, HH
Logemann, F
Bange, FC
Schmidt, RE
Stoll, M
author_sort Mohammad-Khani, S
collection PubMed
description Cryptococcus neoformans is the most common cause of life threatening meningoencephalitis in HIV-infected patients. Diagnosis is based on tests for cryptoccocal antigen in serum and cerebrospinal fluid, and on culture of the organism. We present a case of AIDS-related cryptococcal meningoencephalitis unresponsive to antifungal combination therapy, despite of evidence of fungal susceptibility in vitro. Significant decreases in cryptococcal antigen titers in serum and cerebrospinal fluid did not correlate with progress in disease and fatal outcome.
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spelling pubmed-33526592012-05-16 A fatal case of AIDS-defining meningoencephalitis by C. Neoformans, sensitive to antifungal therapy Mohammad-Khani, S Otremba, B Klein, R Capelle, HH Logemann, F Bange, FC Schmidt, RE Stoll, M Eur J Med Res Case Report Cryptococcus neoformans is the most common cause of life threatening meningoencephalitis in HIV-infected patients. Diagnosis is based on tests for cryptoccocal antigen in serum and cerebrospinal fluid, and on culture of the organism. We present a case of AIDS-related cryptococcal meningoencephalitis unresponsive to antifungal combination therapy, despite of evidence of fungal susceptibility in vitro. Significant decreases in cryptococcal antigen titers in serum and cerebrospinal fluid did not correlate with progress in disease and fatal outcome. BioMed Central 2010-11-25 /pmc/articles/PMC3352659/ /pubmed/21159575 http://dx.doi.org/10.1186/2047-783X-15-11-504 Text en Copyright ©2010 I. Holzapfel Publishers
spellingShingle Case Report
Mohammad-Khani, S
Otremba, B
Klein, R
Capelle, HH
Logemann, F
Bange, FC
Schmidt, RE
Stoll, M
A fatal case of AIDS-defining meningoencephalitis by C. Neoformans, sensitive to antifungal therapy
title A fatal case of AIDS-defining meningoencephalitis by C. Neoformans, sensitive to antifungal therapy
title_full A fatal case of AIDS-defining meningoencephalitis by C. Neoformans, sensitive to antifungal therapy
title_fullStr A fatal case of AIDS-defining meningoencephalitis by C. Neoformans, sensitive to antifungal therapy
title_full_unstemmed A fatal case of AIDS-defining meningoencephalitis by C. Neoformans, sensitive to antifungal therapy
title_short A fatal case of AIDS-defining meningoencephalitis by C. Neoformans, sensitive to antifungal therapy
title_sort fatal case of aids-defining meningoencephalitis by c. neoformans, sensitive to antifungal therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352659/
https://www.ncbi.nlm.nih.gov/pubmed/21159575
http://dx.doi.org/10.1186/2047-783X-15-11-504
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