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Association Between Genetic Variants on Chromosome 15q25 Locus and Objective Measures of Tobacco Exposure

BACKGROUND: Two single-nucleotide polymorphisms, rs1051730 and rs16969968, located within the nicotinic acetylcholine receptor gene cluster on chromosome 15q25 locus, are associated with heaviness of smoking, risk for lung cancer, and other smoking-related health outcomes. Previous studies have typi...

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Detalles Bibliográficos
Autores principales:	Munafò, Marcus R., Timofeeva, Maria N., Morris, Richard W., Prieto-Merino, David, Sattar, Naveed, Brennan, Paul, Johnstone, Elaine C., Relton, Caroline, Johnson, Paul C. D., Walther, Donna, Whincup, Peter H., Casas, Juan P., Uhl, George R., Vineis, Paolo, Padmanabhan, Sandosh, Jefferis, Barbara J., Amuzu, Antoinette, Riboli, Elio, Upton, Mark N., Aveyard, Paul, Ebrahim, Shah, Hingorani, Aroon D., Watt, Graham, Palmer, Tom M., Timpson, Nicholas J., Davey Smith, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352832/ https://www.ncbi.nlm.nih.gov/pubmed/22534784 http://dx.doi.org/10.1093/jnci/djs191

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