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Cystatin A, a Potential Common Link for Mutant Myocilin Causative Glaucoma

Myocilin (MYOC) is a 504 aa secreted glycoprotein induced by stress factors in the trabecular meshwork tissue of the eye, where it was discovered. Mutations in MYOC are linked to glaucoma. The glaucoma phenotype of each of the different MYOC mutation varies, but all of them cause elevated intraocula...

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Detalles Bibliográficos
Autores principales: Kennedy, K. David, AnithaChristy, S. A., Buie, LaKisha K., Borrás, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352898/
https://www.ncbi.nlm.nih.gov/pubmed/22615763
http://dx.doi.org/10.1371/journal.pone.0036301

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