Cargando…

Cyclosporin A Inhibits the Influenza Virus Replication through Cyclophilin A-Dependent and -Independent Pathways

The immunosuppressive drug cyclosporin A (CsA) has inhibitory effects on the replication of several viruses. The antiviral effects are through targeting the interaction between viral proteins and host factor cyclophilin A (CypA). CypA has been identified to interact with influenza A virus M1 protein...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xiaoling, Zhao, Zhendong, Li, Zheng, Xu, Chongfeng, Sun, Lei, Chen, Jilong, Liu, Wenjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352910/ https://www.ncbi.nlm.nih.gov/pubmed/22615963 http://dx.doi.org/10.1371/journal.pone.0037277

Ejemplares similares

Cyclophilin A Restricts Influenza A Virus Replication through Degradation of the M1 Protein
por: Liu, Xiaoling, et al.
Publicado: (2012)

Chicken cyclophilin A is an inhibitory factor to influenza virus replication
por: Xu, Chongfeng, et al.
Publicado: (2010)

Cyclophilin E Functions as a Negative Regulator to Influenza Virus Replication by Impairing the Formation of the Viral Ribonucleoprotein Complex
por: Wang, Zengfu, et al.
Publicado: (2011)

Insights into the Roles of Cyclophilin A During Influenza Virus Infection
por: Liu, Xiaoling, et al.
Publicado: (2013)

Cyclosporine A Regulates Influenza A Virus-induced Macrophages Polarization and Inflammatory Responses by Targeting Cyclophilin A
por: Bai, Xiaoyuan, et al.
Publicado: (2022)

Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir
por: Carbajo-Lozoya, Javier, et al.
Publicado: (2014)

Cyclophilins and cyclophilin inhibitors in nidovirus replication
por: de Wilde, Adriaan H., et al.
Publicado: (2018)

Cyclosporine A-Sensitive, Cyclophilin B-Dependent Endoplasmic Reticulum-Associated Degradation
por: Bernasconi, Riccardo, et al.
Publicado: (2010)

Structural Basis for Cyclosporin Isoform-Specific Inhibition of Cyclophilins from Toxoplasma gondii
por: Favretto, Filippo, et al.
Publicado: (2023)

Conformational Heterogeneity of Cyclosporin A in Cyclophilin 18 Binding
por: Lin, Weilin, et al.
Publicado: (2016)

Cyclophilin A protects mice against infection by influenza A virus
por: Li, Jing, et al.
Publicado: (2016)

Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses
por: Liu, Wei, et al.
Publicado: (2017)

A Major Determinant of Cyclophilin Dependence and Cyclosporine Susceptibility of Hepatitis C Virus Identified by a Genetic Approach
por: Yang, Feng, et al.
Publicado: (2010)

Cyclophilin B facilitates the replication of Orf virus
por: Zhao, Kui, et al.
Publicado: (2017)

Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?
Publicado: (1991)

Characterization of Folding Cores in the Cyclophilin A-Cyclosporin A Complex
por: Heal, Jack W., et al.
Publicado: (2015)

Inhibition of Cyclophilin A on the replication of red spotted grouper nervous necrosis virus associates with multiple pro-inflammatory factors
por: Asim, Muhammad, et al.
Publicado: (2019)

Cyclosporine Inhibits a Direct Interaction between Cyclophilins and Hepatitis C NS5A
por: Fernandes, Fiona, et al.
Publicado: (2010)

Cyclophilins as Modulators of Viral Replication
por: Frausto, Stephen D., et al.
Publicado: (2013)

Cyclophilin A Interacts with Viral VP4 and Inhibits the Replication of Infectious Bursal Disease Virus
por: Wang, Nian, et al.
Publicado: (2015)

Feline coronavirus replication is affected by both cyclophilin A and cyclophilin B
por: Tanaka, Yoshikazu, et al.
Publicado: (2017)

Keratinocyte Secretion of Cyclophilin B via the Constitutive Pathway Is Regulated through Its Cyclosporin-Binding Site
por: Fearon, Paula, et al.
Publicado: (2011)

Identification and characterization of a cyclosporin binding cyclophilin from Staphylococcus aureus Newman
por: Polley, Soumitra, et al.
Publicado: (2017)

Influences of cyclosporin A and non-immunosuppressive derivatives on cellular cyclophilins and viral nucleocapsid protein during human coronavirus 229E replication
por: Ma-Lauer, Yue, et al.
Publicado: (2020)

Suppression of Coronavirus Replication by Cyclophilin Inhibitors
por: Tanaka, Yoshikazu, et al.
Publicado: (2013)

The Cyclophilin-Dependent Calcineurin Inhibitor Voclosporin Inhibits SARS-CoV-2 Replication in Cell Culture
por: Ogando, Natacha S., et al.
Publicado: (2022)

Latent Membrane Protein 1 of Epstein–Barr Virus Promotes RIG-I Degradation Mediated by Proteasome Pathway
por: Xu, Chongfeng, et al.
Publicado: (2018)

Mitochondrial targeting of cyclosporin A enables selective inhibition of cyclophilin-D and enhanced cytoprotection after glucose and oxygen deprivation
por: Malouitre, Sylvanie, et al.
Publicado: (2009)

Inhibition of cyclophilin D by cyclosporin A promotes retinal ganglion cell survival by preventing mitochondrial alteration in ischemic injury
por: Kim, S Y, et al.
Publicado: (2014)

PROTAC targeting cyclophilin A controls virus-induced cytokine storm
por: Li, Heqiao, et al.
Publicado: (2023)

Identification and characterization of novel Plasmodium falciparum cyclophilins and their roles in the antimalarial actions of cyclosporin A and derivatives
por: Marin-Menendez, Alejandro, et al.
Publicado: (2010)

A BAX/BAK and Cyclophilin D-Independent Intrinsic Apoptosis Pathway
por: Zamorano, Sebastián, et al.
Publicado: (2012)

The cyclophilin inhibitor CRV431 prevents both cyclophilin A-HBx complex formation and HBV replication
por: Foster, R.T., et al.
Publicado: (2017)

Cyclosporin A Treatment of Leishmania donovani Reveals Stage-Specific Functions of Cyclophilins in Parasite Proliferation and Viability
por: Yau, Wai-Lok, et al.
Publicado: (2010)

Cyclosporin A Inhibits Rotavirus Replication and Restores Interferon-Beta Signaling Pathway In Vitro and In Vivo
por: Shen, Zigang, et al.
Publicado: (2013)

Cyclosporin A Associated Helicase-Like Protein Facilitates the Association of Hepatitis C Virus RNA Polymerase with Its Cellular Cyclophilin B
por: Morohashi, Kengo, et al.
Publicado: (2011)

Inhibition of Influenza Virus Replication by Targeting Broad Host Cell Pathways
por: Marois, Isabelle, et al.
Publicado: (2014)

Cyclophilin polymorphism and virus infection
por: von Hahn, Thomas, et al.
Publicado: (2015)

Nuclear Envelope Protein SUN2 Promotes Cyclophilin-A-Dependent Steps of HIV Replication
por: Lahaye, Xavier, et al.
Publicado: (2016)

Coronaviruses and arteriviruses display striking differences in their cyclophilin A-dependence during replication in cell culture
por: de Wilde, Adriaan H., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_tq6nvurrfe3nhhpq8f2ua67vld