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Targeting FGFR4 Inhibits Hepatocellular Carcinoma in Preclinical Mouse Models

The fibroblast growth factor (FGF)-FGF receptor (FGFR) signaling system plays critical roles in a variety of normal developmental and physiological processes. It is also well documented that dysregulation of FGF-FGFR signaling may have important roles in tumor development and progression. The FGFR4–...

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Detalles Bibliográficos
Autores principales: French, Dorothy M., Lin, Benjamin C., Wang, Manping, Adams, Camellia, Shek, Theresa, Hötzel, Kathy, Bolon, Brad, Ferrando, Ronald, Blackmore, Craig, Schroeder, Kurt, Rodriguez, Luis A., Hristopoulos, Maria, Venook, Rayna, Ashkenazi, Avi, Desnoyers, Luc R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352934/
https://www.ncbi.nlm.nih.gov/pubmed/22615798
http://dx.doi.org/10.1371/journal.pone.0036713