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RhoA: A therapeutic target for chronic myeloid leukemia

BACKGROUND: Chronic Myeloid Leukemia (CML) is a malignant pluripotent stem cells disorder of myeloid cells. In CML patients, polymorphonuclear leukocytes (PMNL) the terminally differentiated cells of myeloid series exhibit defects in several actin dependent functions such as adhesion, motility, chem...

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Detalles Bibliográficos
Autores principales: Molli, Poonam R, Pradhan, Madhura B, Advani, Suresh H, Naik, Nishigandha R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353160/
https://www.ncbi.nlm.nih.gov/pubmed/22443473
http://dx.doi.org/10.1186/1476-4598-11-16