Acute morphine induces matrix metalloproteinase-9 up-regulation in primary sensory neurons to mask opioid-induced analgesia in mice

BACKGROUND: Despite decades of intense research efforts, actions of acute opioids are not fully understood. Increasing evidence suggests that in addition to well-documented antinociceptive effects opioids also produce paradoxical hyperalgesic and excitatory effects on neurons. However, most studies...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yen-Chin, Berta, Temugin, Liu, Tong, Tan, Ping-Heng, Ji, Ru-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353172/
https://www.ncbi.nlm.nih.gov/pubmed/22444868
http://dx.doi.org/10.1186/1744-8069-8-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353172/
https://www.ncbi.nlm.nih.gov/pubmed/22444868
http://dx.doi.org/10.1186/1744-8069-8-19

Ejemplares similares