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High glucose concentrations induce TNF-α production through the down-regulation of CD33 in primary human monocytes

BACKGROUND: CD33 is a membrane receptor containing a lectin domain and a cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM) that is able to inhibit cytokine production. CD33 is expressed by monocytes, and reduced expression of CD33 correlates with augmented production of inflammatory...

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Detalles Bibliográficos
Autores principales:	Gonzalez, Yolanda, Herrera, M Teresa, Soldevila, Gloria, Garcia-Garcia, Lourdes, Fabián, Guadalupe, Pérez-Armendariz, E Martha, Bobadilla, Karen, Guzmán-Beltrán, Silvia, Sada, Eduardo, Torres, Martha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353220/ https://www.ncbi.nlm.nih.gov/pubmed/22500980 http://dx.doi.org/10.1186/1471-2172-13-19

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