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Distribution of human CYP2C8*2 allele in three different African populations

BACKGROUND: The aim of this study was to investigate cytochrome P450 2C8*2 (CYP2C8*2) distribution and allele frequency in three populations from West and East Africa exposed to Plasmodium falciparum malaria. CYP2C8 enzyme is involved in the metabolism of the anti-malarials amodiaquine and chloroqui...

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Detalles Bibliográficos
Autores principales:	Paganotti, Giacomo M, Gramolelli, Silvia, Tabacchi, Francesca, Russo, Gianluca, Modiano, David, Coluzzi, Mario, Romano, Rita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353233/ https://www.ncbi.nlm.nih.gov/pubmed/22531455 http://dx.doi.org/10.1186/1475-2875-11-125

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