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Beta catenin and cytokine pathway dysregulation in patients with manifestations of the "PTEN hamartoma tumor syndrome"

BACKGROUND: The "PTEN hamartoma tumor syndrome" (PHTS) includes a group of syndromes caused by germline mutations within the tumor suppressor gene "phosphatase and tensin homolog deleted on chromosome ten" (PTEN), characterized by multiple polyps in the gastrointestinal tract and...

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Detalles Bibliográficos
Autores principales: Galatola, Martina, Paparo, Lorella, Duraturo, Francesca, Turano, Mimmo, Rossi, Giovanni Battista, Izzo, Paola, De Rosa, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353236/
https://www.ncbi.nlm.nih.gov/pubmed/22520842
http://dx.doi.org/10.1186/1471-2350-13-28