Oxygen radical-mediated oxidation reactions of an alanine peptide motif - density functional theory and transition state theory study

BACKGROUND: Oxygen-base (O-base) oxidation in protein backbone is important in the protein backbone fragmentation due to the attack from reactive oxygen species (ROS). In this study, an alanine peptide was used model system to investigate this O-base oxidation by employing density functional theory...

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Detalles Bibliográficos
Autores principales: Chen, Hsing-Yu, Jang, Soonmin, Jinn, Tzyy-Rong, Chang, Jia-Yaw, Lu, Hsiu-Feng, Li, Feng-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353240/
https://www.ncbi.nlm.nih.gov/pubmed/22524792
http://dx.doi.org/10.1186/1752-153X-6-33

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