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PKC-δ mediates interferon-α-induced apoptosis through c-Jun NH(2)-terminal kinase activation

BACKGROUND: Interferon-α (IFN-α) exerts an anti-tumor effect at least through induction of apoptosis in a variety of types including B lymphoma cells. We recently found that IFN-α induced a sustained activation of c-Jun NH(2)-terminal kinase1 (JNK1), which is implicated in activation of the tumor ne...

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Detalles Bibliográficos
Autores principales:	Yanase, Noriko, Hayashida, Miho, Kanetaka-Naka, Yuki, Hoshika, Akinori, Mizuguchi, Junichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353249/ https://www.ncbi.nlm.nih.gov/pubmed/22435755 http://dx.doi.org/10.1186/1471-2121-13-7

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