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A mechanistic basis for potent, glycoprotein B-directed gammaherpesvirus neutralization

Glycoprotein B (gB) is a conserved, essential component of gammaherpes virions and so potentially vulnerable to neutralization. However, few good gB-specific neutralizing antibodies have been identified. Here, we show that murid herpesvirus 4 is strongly neutralized by mAbs that recognize an epitope...

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Detalles Bibliográficos
Autores principales: Glauser, Daniel L., Kratz, Anne-Sophie, Gillet, Laurent, Stevenson, Philip G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353389/
https://www.ncbi.nlm.nih.gov/pubmed/21593277
http://dx.doi.org/10.1099/vir.0.032177-0