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Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy
Objective. To evaluate the effect of maternal smoking during pregnancy on levels of umbilical cord erythropoietin. Methods. Erythropoietin levels were measured in umbilical cord sera of 60 newborns who were delivered vaginally at term. There were 20 (33%) smoking and 40 (67%) nonsmoking mothers. Res...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Scientific World Journal
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353477/ https://www.ncbi.nlm.nih.gov/pubmed/22623897 http://dx.doi.org/10.1100/2012/420763 |
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author | Sazak, Soner Kayıran, Sinan Mahir Paksoy, Yahya |
author_facet | Sazak, Soner Kayıran, Sinan Mahir Paksoy, Yahya |
author_sort | Sazak, Soner |
collection | PubMed |
description | Objective. To evaluate the effect of maternal smoking during pregnancy on levels of umbilical cord erythropoietin. Methods. Erythropoietin levels were measured in umbilical cord sera of 60 newborns who were delivered vaginally at term. There were 20 (33%) smoking and 40 (67%) nonsmoking mothers. Results. Mean cord serum erythropoietin levels were significantly lower in the nonsmokers (nonsmokers, 24 ± 9 IU/L; smokers, 61 ± 46 IU/L; P < .001). There was a significant positive correlation between the number of cigarettes smoked per day and cord serum erythropoietin levels (r, 0.58; P ≤ .05). Conclusions. Smoking during pregnancy is associated with increased levels of umbilical cord erythropoietin at birth. This may indicate a risk of fetal hypoxia and growth restriction. Education and encouragement of cessation of smoking during pregnancy are important to avoid associated fetal and maternal morbidity and mortality. |
format | Online Article Text |
id | pubmed-3353477 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | The Scientific World Journal |
record_format | MEDLINE/PubMed |
spelling | pubmed-33534772012-05-23 Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy Sazak, Soner Kayıran, Sinan Mahir Paksoy, Yahya ScientificWorldJournal Clinical Study Objective. To evaluate the effect of maternal smoking during pregnancy on levels of umbilical cord erythropoietin. Methods. Erythropoietin levels were measured in umbilical cord sera of 60 newborns who were delivered vaginally at term. There were 20 (33%) smoking and 40 (67%) nonsmoking mothers. Results. Mean cord serum erythropoietin levels were significantly lower in the nonsmokers (nonsmokers, 24 ± 9 IU/L; smokers, 61 ± 46 IU/L; P < .001). There was a significant positive correlation between the number of cigarettes smoked per day and cord serum erythropoietin levels (r, 0.58; P ≤ .05). Conclusions. Smoking during pregnancy is associated with increased levels of umbilical cord erythropoietin at birth. This may indicate a risk of fetal hypoxia and growth restriction. Education and encouragement of cessation of smoking during pregnancy are important to avoid associated fetal and maternal morbidity and mortality. The Scientific World Journal 2012-05-01 /pmc/articles/PMC3353477/ /pubmed/22623897 http://dx.doi.org/10.1100/2012/420763 Text en Copyright © 2012 Soner Sazak et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Study Sazak, Soner Kayıran, Sinan Mahir Paksoy, Yahya Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy |
title | Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy |
title_full | Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy |
title_fullStr | Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy |
title_full_unstemmed | Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy |
title_short | Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy |
title_sort | umbilical cord serum erythropoietin levels and maternal smoking in pregnancy |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353477/ https://www.ncbi.nlm.nih.gov/pubmed/22623897 http://dx.doi.org/10.1100/2012/420763 |
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