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Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy

Objective. To evaluate the effect of maternal smoking during pregnancy on levels of umbilical cord erythropoietin. Methods. Erythropoietin levels were measured in umbilical cord sera of 60 newborns who were delivered vaginally at term. There were 20 (33%) smoking and 40 (67%) nonsmoking mothers. Res...

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Detalles Bibliográficos
Autores principales: Sazak, Soner, Kayıran, Sinan Mahir, Paksoy, Yahya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353477/
https://www.ncbi.nlm.nih.gov/pubmed/22623897
http://dx.doi.org/10.1100/2012/420763
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author Sazak, Soner
Kayıran, Sinan Mahir
Paksoy, Yahya
author_facet Sazak, Soner
Kayıran, Sinan Mahir
Paksoy, Yahya
author_sort Sazak, Soner
collection PubMed
description Objective. To evaluate the effect of maternal smoking during pregnancy on levels of umbilical cord erythropoietin. Methods. Erythropoietin levels were measured in umbilical cord sera of 60 newborns who were delivered vaginally at term. There were 20 (33%) smoking and 40 (67%) nonsmoking mothers. Results. Mean cord serum erythropoietin levels were significantly lower in the nonsmokers (nonsmokers, 24 ± 9 IU/L; smokers, 61 ± 46 IU/L; P < .001). There was a significant positive correlation between the number of cigarettes smoked per day and cord serum erythropoietin levels (r, 0.58; P ≤ .05). Conclusions. Smoking during pregnancy is associated with increased levels of umbilical cord erythropoietin at birth. This may indicate a risk of fetal hypoxia and growth restriction. Education and encouragement of cessation of smoking during pregnancy are important to avoid associated fetal and maternal morbidity and mortality.
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spelling pubmed-33534772012-05-23 Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy Sazak, Soner Kayıran, Sinan Mahir Paksoy, Yahya ScientificWorldJournal Clinical Study Objective. To evaluate the effect of maternal smoking during pregnancy on levels of umbilical cord erythropoietin. Methods. Erythropoietin levels were measured in umbilical cord sera of 60 newborns who were delivered vaginally at term. There were 20 (33%) smoking and 40 (67%) nonsmoking mothers. Results. Mean cord serum erythropoietin levels were significantly lower in the nonsmokers (nonsmokers, 24 ± 9 IU/L; smokers, 61 ± 46 IU/L; P < .001). There was a significant positive correlation between the number of cigarettes smoked per day and cord serum erythropoietin levels (r, 0.58; P ≤ .05). Conclusions. Smoking during pregnancy is associated with increased levels of umbilical cord erythropoietin at birth. This may indicate a risk of fetal hypoxia and growth restriction. Education and encouragement of cessation of smoking during pregnancy are important to avoid associated fetal and maternal morbidity and mortality. The Scientific World Journal 2012-05-01 /pmc/articles/PMC3353477/ /pubmed/22623897 http://dx.doi.org/10.1100/2012/420763 Text en Copyright © 2012 Soner Sazak et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Sazak, Soner
Kayıran, Sinan Mahir
Paksoy, Yahya
Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy
title Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy
title_full Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy
title_fullStr Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy
title_full_unstemmed Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy
title_short Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy
title_sort umbilical cord serum erythropoietin levels and maternal smoking in pregnancy
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353477/
https://www.ncbi.nlm.nih.gov/pubmed/22623897
http://dx.doi.org/10.1100/2012/420763
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