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Study of the Activity of 3-benzyl-5-(4-chloro-arylazo)-4-thioxo-imidazolidin-2-one against Schistosomiasis Mansoni in Mice

Previous studies conducted with the imidazolidinic derivative 3-benzyl-5-(4-chloro-arylazo)-4-thioxo-imidazolidin-2-one (LPSF-PT05) show outstanding activity against adult Schistosoma mansoni worms in vitro. In the first phase of this study, S. mansoni-infected mice were treated, orally, with 100 mg...

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Detalles Bibliográficos
Autores principales: da Silva, Andréa Cristina Apolinário, Neves, Juliana Kelle de Andrade Lemoine, Irmão, João Inácio, Costa, Vláudia Maria Assis, Souza, Valdênia Maria Oliveira, de Medeiros, Paloma Lys, da Silva, Eliete Cavalcanti, de Lima, Maria do Carmo Alves, Pitta, Ivan da Rocha, Albuquerque, Mônica Camelo Pessoa de Azevedo, Galdino, Suely Lins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353485/
https://www.ncbi.nlm.nih.gov/pubmed/22623908
http://dx.doi.org/10.1100/2012/520524