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Office-based Slit-lamp Needle Revision with Adjunctive Mitomycin-C for Late Failed or Encapsulated Filtering Blebs
PURPOSE: The purpose of this study was to assess the results of bleb needling in glaucomatous patients with late failed filtering blebs. MATERIALS AND METHODS: A retrospective case series of 27 eyes of 27 patients was considered. All patients underwent needle bleb revision with adjuvant mitomycin-C...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353671/ https://www.ncbi.nlm.nih.gov/pubmed/22623862 http://dx.doi.org/10.4103/0974-9233.95255 |
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author | Amini, Heidar Esmaili, Alireza Zarei, Reza Amini, Nima Daneshvar, Ramin |
author_facet | Amini, Heidar Esmaili, Alireza Zarei, Reza Amini, Nima Daneshvar, Ramin |
author_sort | Amini, Heidar |
collection | PubMed |
description | PURPOSE: The purpose of this study was to assess the results of bleb needling in glaucomatous patients with late failed filtering blebs. MATERIALS AND METHODS: A retrospective case series of 27 eyes of 27 patients was considered. All patients underwent needle bleb revision with adjuvant mitomycin-C performed at the slit lamp, during an office visit. Complete success was defined as postneedling intraocular pressure (IOP) ≤ 21 mmHg without any antiglaucoma medications and qualified success was IOP ≤ 21 mmHg with topical antiglaucoma medications. RESULTS: There were 12 eyes with encapsulated blebs and 15 eyes with flat blebs. The mean interval between index filtering surgery and bleb revision was 32.74 ± 15.36 months. Mean IOP was 25.07 ± 4.80 mmHg before surgery and 19.66 ± 4.97 mmHg at last postoperative follow-up. The mean follow-up was 20.31 ± 15.63 months. Complete and qualified successes were 7.4% and 51.9%, respectively. Cumulative rates of success at 1, 2, 3, and 4 years were 76%, 65%, 49%, and 37%, respectively. The mean number of antiglaucoma medications was reduced from 3.15 ± 0.36 preoperatively to 2.33 ± 1.21 postoperatively (P<0.001). CONCLUSION: Slit-lamp needle revision in office is a simple and effective method for treating late encapsulated or flat filtering blebs without significant complications even for late bleb failure. |
format | Online Article Text |
id | pubmed-3353671 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-33536712012-05-23 Office-based Slit-lamp Needle Revision with Adjunctive Mitomycin-C for Late Failed or Encapsulated Filtering Blebs Amini, Heidar Esmaili, Alireza Zarei, Reza Amini, Nima Daneshvar, Ramin Middle East Afr J Ophthalmol Original Article PURPOSE: The purpose of this study was to assess the results of bleb needling in glaucomatous patients with late failed filtering blebs. MATERIALS AND METHODS: A retrospective case series of 27 eyes of 27 patients was considered. All patients underwent needle bleb revision with adjuvant mitomycin-C performed at the slit lamp, during an office visit. Complete success was defined as postneedling intraocular pressure (IOP) ≤ 21 mmHg without any antiglaucoma medications and qualified success was IOP ≤ 21 mmHg with topical antiglaucoma medications. RESULTS: There were 12 eyes with encapsulated blebs and 15 eyes with flat blebs. The mean interval between index filtering surgery and bleb revision was 32.74 ± 15.36 months. Mean IOP was 25.07 ± 4.80 mmHg before surgery and 19.66 ± 4.97 mmHg at last postoperative follow-up. The mean follow-up was 20.31 ± 15.63 months. Complete and qualified successes were 7.4% and 51.9%, respectively. Cumulative rates of success at 1, 2, 3, and 4 years were 76%, 65%, 49%, and 37%, respectively. The mean number of antiglaucoma medications was reduced from 3.15 ± 0.36 preoperatively to 2.33 ± 1.21 postoperatively (P<0.001). CONCLUSION: Slit-lamp needle revision in office is a simple and effective method for treating late encapsulated or flat filtering blebs without significant complications even for late bleb failure. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3353671/ /pubmed/22623862 http://dx.doi.org/10.4103/0974-9233.95255 Text en Copyright: © Middle East African Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Amini, Heidar Esmaili, Alireza Zarei, Reza Amini, Nima Daneshvar, Ramin Office-based Slit-lamp Needle Revision with Adjunctive Mitomycin-C for Late Failed or Encapsulated Filtering Blebs |
title | Office-based Slit-lamp Needle Revision with Adjunctive Mitomycin-C for Late Failed or Encapsulated Filtering Blebs |
title_full | Office-based Slit-lamp Needle Revision with Adjunctive Mitomycin-C for Late Failed or Encapsulated Filtering Blebs |
title_fullStr | Office-based Slit-lamp Needle Revision with Adjunctive Mitomycin-C for Late Failed or Encapsulated Filtering Blebs |
title_full_unstemmed | Office-based Slit-lamp Needle Revision with Adjunctive Mitomycin-C for Late Failed or Encapsulated Filtering Blebs |
title_short | Office-based Slit-lamp Needle Revision with Adjunctive Mitomycin-C for Late Failed or Encapsulated Filtering Blebs |
title_sort | office-based slit-lamp needle revision with adjunctive mitomycin-c for late failed or encapsulated filtering blebs |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353671/ https://www.ncbi.nlm.nih.gov/pubmed/22623862 http://dx.doi.org/10.4103/0974-9233.95255 |
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