Multiple Interferon Stimulated Genes Synergize with the Zinc Finger Antiviral Protein to Mediate Anti-Alphavirus Activity

The zinc finger antiviral protein (ZAP) is a host factor that mediates inhibition of viruses in the Filoviridae, Retroviridae and Togaviridae families. We previously demonstrated that ZAP blocks replication of Sindbis virus (SINV), the prototype Alphavirus in the Togaviridae family at an early step...

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Detalles Bibliográficos
Autores principales: Karki, Sophiya, Li, Melody M. H., Schoggins, John W., Tian, Suyan, Rice, Charles M., MacDonald, Margaret R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353916/
https://www.ncbi.nlm.nih.gov/pubmed/22615998
http://dx.doi.org/10.1371/journal.pone.0037398

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