Cargando…
A General Strategy to Endow Natural Fusion-protein-Derived Peptides with Potent Antiviral Activity
Fusion between the viral and target cell membranes is an obligatory step for the infectivity of all enveloped virus, and blocking this process is a clinically validated therapeutic strategy. Viral fusion is driven by specialized proteins which, although specific to each virus, act through a common m...
Autores principales: | Pessi, Antonello, Langella, Annunziata, Capitò, Elena, Ghezzi, Silvia, Vicenzi, Elisa, Poli, Guido, Ketas, Thomas, Mathieu, Cyrille, Cortese, Riccardo, Horvat, Branka, Moscona, Anne, Porotto, Matteo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353973/ https://www.ncbi.nlm.nih.gov/pubmed/22666328 http://dx.doi.org/10.1371/journal.pone.0036833 |
Ejemplares similares
-
Fusion Inhibitory Lipopeptides Engineered for Prophylaxis of Nipah Virus in Primates
por: Mathieu, Cyrille, et al.
Publicado: (2018) -
Rapid Screening for Entry Inhibitors of Highly Pathogenic Viruses under Low-Level Biocontainment
por: Talekar, Aparna, et al.
Publicado: (2012) -
Measles Fusion Machinery Is Dysregulated in Neuropathogenic Variants
por: Jurgens, Eric M., et al.
Publicado: (2015) -
Broad spectrum antiviral activity for paramyxoviruses is modulated by biophysical properties of fusion inhibitory peptides
por: Mathieu, Cyrille, et al.
Publicado: (2017) -
Inhibition of Nipah Virus Infection In Vivo: Targeting an Early Stage of Paramyxovirus Fusion Activation during Viral Entry
por: Porotto, Matteo, et al.
Publicado: (2010)