Cargando…
The Loss of Functional Caspase-12 in Europe Is a Pre-Neolithic Event
BACKGROUND: Caspase-12 (CASP12) modulates the susceptibility to sepsis. In humans, the “C” allele at CASP12 rs497116 has been associated with an increased risk of sepsis. Instead, the derived “T” allele encodes for an inactive caspase-12. Interestingly, Eurasians are practically fixed for the inacti...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353979/ https://www.ncbi.nlm.nih.gov/pubmed/22615879 http://dx.doi.org/10.1371/journal.pone.0037022 |