WW domain-containing oxidoreductase promotes neuronal differentiation via negative regulation of glycogen synthase kinase 3β

WW domain-containing oxidoreductase (WWOX), a putative tumour suppressor, is suggested to be involved in the hyperphosphorylation of Alzheimer's Tau. Tau is a microtubule-associated protein that has an important role in microtubule assembly and stability. Glycogen synthase kinase 3β (GSK3β) has...

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Detalles Bibliográficos
Autores principales: Wang, H-Y, Juo, L-I, Lin, Y-T, Hsiao, M, Lin, J-T, Tsai, C-H, Tzeng, Y-H, Chuang, Y-C, Chang, N-S, Yang, C-N, Lu, P-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354054/
https://www.ncbi.nlm.nih.gov/pubmed/22193544
http://dx.doi.org/10.1038/cdd.2011.188

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