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Cognition in Rapid Eye Movement Sleep Behavior Disorder
Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by excessive muscle activity and undesirable motor events during REM sleep. RBD occurs in approximately 0.5% of the general population, with a higher prevalence in older men. RBD is a frequent feature of dementia wi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354332/ https://www.ncbi.nlm.nih.gov/pubmed/22629254 http://dx.doi.org/10.3389/fneur.2012.00082 |
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author | Gagnon, Jean-François Bertrand, Josie-Anne Génier Marchand, Daphné |
author_facet | Gagnon, Jean-François Bertrand, Josie-Anne Génier Marchand, Daphné |
author_sort | Gagnon, Jean-François |
collection | PubMed |
description | Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by excessive muscle activity and undesirable motor events during REM sleep. RBD occurs in approximately 0.5% of the general population, with a higher prevalence in older men. RBD is a frequent feature of dementia with Lewy bodies (DLB), but is only rarely reported in Alzheimer’s disease. RBD is also a risk factor for α-synuclein-related diseases, such as DLB, Parkinson’s disease (PD), and multiple system atrophy. Therefore, RBD has major implications for the diagnosis and treatment of neurodegenerative disorders and for understanding specific neurodegeneration patterns. Several markers of neurodegeneration have been identified in RBD, including cognitive impairments such as deficits in attention, executive functions, learning capacities, and visuospatial abilities. Approximately 50% of RBD patients present mild cognitive impairment. Moreover, RBD is also associated with cognitive decline in PD. |
format | Online Article Text |
id | pubmed-3354332 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Frontiers Research Foundation |
record_format | MEDLINE/PubMed |
spelling | pubmed-33543322012-05-24 Cognition in Rapid Eye Movement Sleep Behavior Disorder Gagnon, Jean-François Bertrand, Josie-Anne Génier Marchand, Daphné Front Neurol Neuroscience Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by excessive muscle activity and undesirable motor events during REM sleep. RBD occurs in approximately 0.5% of the general population, with a higher prevalence in older men. RBD is a frequent feature of dementia with Lewy bodies (DLB), but is only rarely reported in Alzheimer’s disease. RBD is also a risk factor for α-synuclein-related diseases, such as DLB, Parkinson’s disease (PD), and multiple system atrophy. Therefore, RBD has major implications for the diagnosis and treatment of neurodegenerative disorders and for understanding specific neurodegeneration patterns. Several markers of neurodegeneration have been identified in RBD, including cognitive impairments such as deficits in attention, executive functions, learning capacities, and visuospatial abilities. Approximately 50% of RBD patients present mild cognitive impairment. Moreover, RBD is also associated with cognitive decline in PD. Frontiers Research Foundation 2012-05-17 /pmc/articles/PMC3354332/ /pubmed/22629254 http://dx.doi.org/10.3389/fneur.2012.00082 Text en Copyright © 2012 Gagnon, Bertrand and Génier Marchand. http://www.frontiersin.org/licenseagreement This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited. |
spellingShingle | Neuroscience Gagnon, Jean-François Bertrand, Josie-Anne Génier Marchand, Daphné Cognition in Rapid Eye Movement Sleep Behavior Disorder |
title | Cognition in Rapid Eye Movement Sleep Behavior Disorder |
title_full | Cognition in Rapid Eye Movement Sleep Behavior Disorder |
title_fullStr | Cognition in Rapid Eye Movement Sleep Behavior Disorder |
title_full_unstemmed | Cognition in Rapid Eye Movement Sleep Behavior Disorder |
title_short | Cognition in Rapid Eye Movement Sleep Behavior Disorder |
title_sort | cognition in rapid eye movement sleep behavior disorder |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354332/ https://www.ncbi.nlm.nih.gov/pubmed/22629254 http://dx.doi.org/10.3389/fneur.2012.00082 |
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