Induction of GADD34 Is Necessary for dsRNA-Dependent Interferon-β Production and Participates in the Control of Chikungunya Virus Infection

Nucleic acid sensing by cells is a key feature of antiviral responses, which generally result in type-I Interferon production and tissue protection. However, detection of double-stranded RNAs in virus-infected cells promotes two concomitant and apparently conflicting events. The dsRNA-dependent prot...

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Detalles Bibliográficos
Autores principales: Clavarino, Giovanna, Cláudio, Nuno, Couderc, Thérèse, Dalet, Alexandre, Judith, Delphine, Camosseto, Voahirana, Schmidt, Enrico K., Wenger, Till, Lecuit, Marc, Gatti, Evelina, Pierre, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355096/
https://www.ncbi.nlm.nih.gov/pubmed/22615568
http://dx.doi.org/10.1371/journal.ppat.1002708

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