Francisella tularensis Elicits IL-10 via a PGE(2)-Inducible Factor, to Drive Macrophage MARCH1 Expression and Class II Down-Regulation

Francisella tularensis is a bacterial pathogen that uses host-derived PGE(2) to subvert the host's adaptive immune responses in multiple ways. Francisella-induced PGE(2) acts directly on CD4 T cells to blunt production of IFN-γ. Francisella-induced PGE(2) can also elicit production of a >10...

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Detalles Bibliográficos
Autores principales: Hunt, Danielle, Wilson, Justin E., Weih, Karis A., Ishido, Satoshi, Harton, Jonathan A., Roche, Paul A., Drake, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355121/
https://www.ncbi.nlm.nih.gov/pubmed/22615981
http://dx.doi.org/10.1371/journal.pone.0037330

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