Uptake Rate of Cationic Mitochondrial Inhibitor MKT-077 Determines Cellular Oxygen Consumption Change in Carcinoma Cells

OBJECTIVE: Since tumor radiation response is oxygen-dependent, radiosensitivity can be enhanced by increasing tumor oxygenation. Theoretically, inhibiting cellular oxygen consumption is the most efficient way to increase oxygen levels. The cationic, rhodacyanine dye-analog MKT-077 inhibits mitochond...

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Detalles Bibliográficos
Autores principales: Chunta, John L., Vistisen, Kerry S., Yazdi, Zeinab, Braun, Rod D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355126/
https://www.ncbi.nlm.nih.gov/pubmed/22616013
http://dx.doi.org/10.1371/journal.pone.0037471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355126/
https://www.ncbi.nlm.nih.gov/pubmed/22616013
http://dx.doi.org/10.1371/journal.pone.0037471

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