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A Novel Function of Noc2 in Agonist-Induced Intracellular Ca(2+) Increase during Zymogen-Granule Exocytosis in Pancreatic Acinar Cells

Noc2, a putative Rab effector, contributes to secretory-granule exocytosis in neuroendocrine and exocrine cells. Here, using two-photon excitation live-cell imaging, we investigated its role in Ca(2+)-dependent zymogen granule (ZG) exocytosis in pancreatic acinar cells from wild-type (WT) and Noc2-k...

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Detalles Bibliográficos
Autores principales:	Ogata, Sho, Miki, Takashi, Seino, Susumu, Tamai, Seiichi, Kasai, Haruo, Nemoto, Tomomi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355174/ https://www.ncbi.nlm.nih.gov/pubmed/22615885 http://dx.doi.org/10.1371/journal.pone.0037048

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