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Impact of diagnostic misclassification on estimation of genetic correlations using genome-wide genotypes
Disorders that share genetic risk factors often are placed in closely related diagnostic categories and treated similarly. Until recently, evidence for shared genetic etiology derived from classical research strategies – coaggregation in family and twin studies. Accumulating sufficient numbers of fa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355255/ https://www.ncbi.nlm.nih.gov/pubmed/22258521 http://dx.doi.org/10.1038/ejhg.2011.257 |