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Impact of diagnostic misclassification on estimation of genetic correlations using genome-wide genotypes

Disorders that share genetic risk factors often are placed in closely related diagnostic categories and treated similarly. Until recently, evidence for shared genetic etiology derived from classical research strategies – coaggregation in family and twin studies. Accumulating sufficient numbers of fa...

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Detalles Bibliográficos
Autores principales: Wray, Naomi R, Lee, Sang Hong, Kendler, Kenneth S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355255/
https://www.ncbi.nlm.nih.gov/pubmed/22258521
http://dx.doi.org/10.1038/ejhg.2011.257