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An evaluation of different meta-analysis approaches in the presence of allelic heterogeneity
Meta-analysis has proven a useful tool in genetic association studies. Allelic heterogeneity can arise from ethnic background differences across populations being meta-analyzed (for example, in search of common frequency variants through genome-wide association studies), and through the presence of...
Autores principales: | Asimit, Jennifer, Day-Williams, Aaron, Zgaga, Lina, Rudan, Igor, Boraska, Vesna, Zeggini, Eleftheria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355266/ https://www.ncbi.nlm.nih.gov/pubmed/22293689 http://dx.doi.org/10.1038/ejhg.2011.274 |
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