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Hepatic and Pulmonary Toxicogenomic Profiles in Mice Intratracheally Instilled With Carbon Black Nanoparticles Reveal Pulmonary Inflammation, Acute Phase Response, and Alterations in Lipid Homeostasis
Global pulmonary and hepatic messenger RNA profiles in adult female C57BL/6 mice intratracheally instilled with carbon black nanoparticles (NPs) (Printex 90) were analyzed to identify biological perturbations underlying systemic responses to NP exposure. Tissue gene expression changes were profiled...
Autores principales: | Bourdon, Julie A., Halappanavar, Sabina, Saber, Anne T., Jacobsen, Nicklas R., Williams, Andrew, Wallin, Håkan, Vogel, Ulla, Yauk, Carole L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355316/ https://www.ncbi.nlm.nih.gov/pubmed/22461453 http://dx.doi.org/10.1093/toxsci/kfs119 |
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