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Plant Glycosyltransferases Beyond CAZy: A Perspective on DUF Families
The carbohydrate active enzyme (CAZy) database is an invaluable resource for glycobiology and currently contains 45 glycosyltransferase families that are represented in plants. Glycosyltransferases (GTs) have many functions in plants, but the majority are likely to be involved in biosynthesis of pol...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355507/ https://www.ncbi.nlm.nih.gov/pubmed/22629278 http://dx.doi.org/10.3389/fpls.2012.00059 |
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author | Hansen, Sara Fasmer Harholt, Jesper Oikawa, Ai Scheller, Henrik V. |
author_facet | Hansen, Sara Fasmer Harholt, Jesper Oikawa, Ai Scheller, Henrik V. |
author_sort | Hansen, Sara Fasmer |
collection | PubMed |
description | The carbohydrate active enzyme (CAZy) database is an invaluable resource for glycobiology and currently contains 45 glycosyltransferase families that are represented in plants. Glycosyltransferases (GTs) have many functions in plants, but the majority are likely to be involved in biosynthesis of polysaccharides and glycoproteins in the plant cell wall. Bioinformatic approaches and structural modeling suggest that a number of protein families in plants include GTs that have not yet been identified as such and are therefore not included in CAZy. These families include proteins with domain of unknown function (DUF) DUF23, DUF246, and DUF266. The evidence for these proteins being GTs and their possible roles in cell wall biosynthesis is discussed. |
format | Online Article Text |
id | pubmed-3355507 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Frontiers Research Foundation |
record_format | MEDLINE/PubMed |
spelling | pubmed-33555072012-05-24 Plant Glycosyltransferases Beyond CAZy: A Perspective on DUF Families Hansen, Sara Fasmer Harholt, Jesper Oikawa, Ai Scheller, Henrik V. Front Plant Sci Plant Science The carbohydrate active enzyme (CAZy) database is an invaluable resource for glycobiology and currently contains 45 glycosyltransferase families that are represented in plants. Glycosyltransferases (GTs) have many functions in plants, but the majority are likely to be involved in biosynthesis of polysaccharides and glycoproteins in the plant cell wall. Bioinformatic approaches and structural modeling suggest that a number of protein families in plants include GTs that have not yet been identified as such and are therefore not included in CAZy. These families include proteins with domain of unknown function (DUF) DUF23, DUF246, and DUF266. The evidence for these proteins being GTs and their possible roles in cell wall biosynthesis is discussed. Frontiers Research Foundation 2012-03-28 /pmc/articles/PMC3355507/ /pubmed/22629278 http://dx.doi.org/10.3389/fpls.2012.00059 Text en Copyright © 2012 Hansen, Harholt, Oikawa and Scheller. http://www.frontiersin.org/licenseagreement This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited. |
spellingShingle | Plant Science Hansen, Sara Fasmer Harholt, Jesper Oikawa, Ai Scheller, Henrik V. Plant Glycosyltransferases Beyond CAZy: A Perspective on DUF Families |
title | Plant Glycosyltransferases Beyond CAZy: A Perspective on DUF Families |
title_full | Plant Glycosyltransferases Beyond CAZy: A Perspective on DUF Families |
title_fullStr | Plant Glycosyltransferases Beyond CAZy: A Perspective on DUF Families |
title_full_unstemmed | Plant Glycosyltransferases Beyond CAZy: A Perspective on DUF Families |
title_short | Plant Glycosyltransferases Beyond CAZy: A Perspective on DUF Families |
title_sort | plant glycosyltransferases beyond cazy: a perspective on duf families |
topic | Plant Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355507/ https://www.ncbi.nlm.nih.gov/pubmed/22629278 http://dx.doi.org/10.3389/fpls.2012.00059 |
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