Cargando…

Radiotherapy and Erlotinib Combined: Review of the Preclinical and Clinical Evidence

Epidermal growth factor receptor (EGFR) is often overexpressed in tumors and has been associated with poor prognosis in some cancer types. The introduction of inhibitors of EGFR, such as erlotinib, represents an important recent advance in the targeted treatment of cancer. Several studies have evalu...

Descripción completa

Detalles Bibliográficos
Autor principal:	Mehta, Vivek K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355822/ https://www.ncbi.nlm.nih.gov/pubmed/22645717 http://dx.doi.org/10.3389/fonc.2012.00031

Ejemplares similares

Clinical and Preclinical Outcomes of Combining Targeted Therapy With Radiotherapy
por: Elbanna, May, et al.
Publicado: (2021)

CpG plus radiotherapy: a review of preclinical works leading to clinical trial
por: Mason, Kathy A., et al.
Publicado: (2012)

Phase II Trial of Erlotinib during and after Radiotherapy in Children with Newly Diagnosed High-Grade Gliomas
por: Qaddoumi, Ibrahim, et al.
Publicado: (2014)

Efficacy and safety of bevacizumab plus erlotinib versus bevacizumab or erlotinib alone in the treatment of non-small-cell lung cancer: a systematic review and meta-analysis
por: Zhang, Shu, et al.
Publicado: (2016)

Erlotinib plus bevacizumab versus erlotinib alone in patients with EGFR-positive advanced non-small-cell lung cancer: a systematic review and meta-analysis of randomised controlled trials
por: Deng, Wusheng, et al.
Publicado: (2022)

Combining the DNA Repair Inhibitor Dbait With Radiotherapy for the Treatment of High Grade Glioma: Efficacy and Protein Biomarkers of Resistance in Preclinical Models
por: Biau, Julian, et al.
Publicado: (2019)

Preclinical and Clinical Evidence of Lurbinectedin in Ovarian Cancer: Current Status and Future Perspectives
por: Musacchio, Lucia, et al.
Publicado: (2022)

The effect of CELLFOOD(TM) on radiotherapy or combined chemoradiotherapy: preclinical evidence
por: Nuvoli, Barbara, et al.
Publicado: (2019)

Inhibition of Immune Checkpoints and Vascular Endothelial Growth Factor as Combination Therapy for Metastatic Melanoma: An Overview of Rationale, Preclinical Evidence, and Initial Clinical Data
por: Ott, Patrick A., et al.
Publicado: (2015)

Clinical Response to Apatinib Combined With Brain Radiotherapy in EGFR Wild-Type and ALK-Negative Lung Adenocarcinoma With Multiple Brain Metastases
por: Ying, Xiaofang, et al.
Publicado: (2020)

Clinical evidence for synergy between immunotherapy and radiotherapy (SITAR)
por: Gill, Suki, et al.
Publicado: (2022)

Combining energy-based focal ablation and immune checkpoint inhibitors: preclinical research and clinical trials
por: Jiang, Minhan, et al.
Publicado: (2023)

Combination of Bempegaldesleukin and Anti-CTLA-4 Prevents Metastatic Dissemination After Primary Resection or Radiotherapy in a Preclinical Model of Non-Small Cell Lung Cancer
por: Bates, Amber M., et al.
Publicado: (2021)

Radiotherapy in Combination With Cytokine Treatment
por: Palata, Ondrej, et al.
Publicado: (2019)

Preclinical Testing of Erlotinib in a Transgenic Alveolar Rhabdomyosarcoma Mouse Model
por: Abraham, Jinu, et al.
Publicado: (2011)

An Extensive Review on Preclinical and Clinical Trials of Oncolytic Viruses Therapy for Pancreatic Cancer
por: Nisar, Maryum, et al.
Publicado: (2022)

Preclinical Evaluation of Intraoperative Low-Energy Photon Radiotherapy Using Spherical Applicators in Locally Advanced Prostate Cancer
por: Buge, François, et al.
Publicado: (2015)

Putative Abscopal Effect in Three Patients Treated by Combined Radiotherapy and Modulated Electrohyperthermia
por: Chi, Mau-Shin, et al.
Publicado: (2020)

Efficacy of erlotinib in NSCLC harboring rare EGFR extracellular domain mutation (T263P) and common mutations: Case report and literature review
por: Wang, Qian, et al.
Publicado: (2022)

Combined effects of bevacizumab with erlotinib and irradiation: a preclinical study on a head and neck cancer orthotopic model
por: Bozec, A, et al.
Publicado: (2008)

Evaluating preclinical evidence for clinical translation in childhood brain tumours: Guidelines from the CONNECT, PNOC, and ITCC brain networks
por: Jones, Chris, et al.
Publicado: (2023)

Retrospective practice review of treatment of metastatic non-small-cell lung cancer with second-line erlotinib
por: Melosky, B., et al.
Publicado: (2008)

Tumor Microenvironment Modifications Recorded With IVIM Perfusion Analysis and DCE-MRI After Neoadjuvant Radiotherapy: A Preclinical Study
por: Lallemand, François, et al.
Publicado: (2021)

Effective Combinations of Immunotherapy and Radiotherapy for Cancer Treatment
por: Yu, Siting, et al.
Publicado: (2022)

The potential of ferroptosis combined with radiotherapy in cancer treatment
por: Lu, Zekun, et al.
Publicado: (2023)

Combination Erlotinib-Cisplatin and Atg3-Mediated Autophagy in Erlotinib Resistant Lung Cancer
por: Lee, Jasmine G., et al.
Publicado: (2012)

Editorial: Intraoperative radiotherapy for gastrointestinal malignancy: updated evidence
por: Masaki, Tadahiko, et al.
Publicado: (2023)

Combined proton radiography and irradiation for high-precision preclinical studies in small animals
por: Schneider, Moritz, et al.
Publicado: (2022)

A Review of Ongoing Trials of Stereotactic Ablative Radiotherapy for Oligometastatic Cancers: Where Will the Evidence Lead?
por: Al-Shafa, Faiez, et al.
Publicado: (2019)

Preclinical evidence of a direct pro-survival role of arginine deprivation in multiple myeloma
por: Trudu, Matteo, et al.
Publicado: (2022)

OPTIMAL and ENSURE trials-based combined cost-effectiveness analysis of erlotinib versus chemotherapy for the first-line treatment of Asian patients with non-squamous non-small-cell lung cancer
por: Wen, Feng, et al.
Publicado: (2018)

The Role of ARL4C in Erlotinib Resistance: Activation of the Jak2/Stat 5/β-Catenin Signaling Pathway
por: Liao, Jinrong, et al.
Publicado: (2020)

A Comparison Between Chemo-Radiotherapy Combined With Immunotherapy and Chemo-Radiotherapy Alone for the Treatment of Newly Diagnosed Glioblastoma: A Systematic Review and Meta-Analysis
por: Lara-Velazquez, Montserrat, et al.
Publicado: (2021)

RONC-07. Fractionated radiotherapy is required to accurately mimic neurostructural late effects in preclinical models
por: Whitehouse, Jacqueline, et al.
Publicado: (2022)

Radiotherapy and Immunotherapy for Head and Neck Cancer: Current Evidence and Challenges
por: Qian, Jack M., et al.
Publicado: (2021)

Immunotherapy Combined with Large Fractions of Radiotherapy: Stereotactic Radiosurgery for Brain Metastases—Implications for Intraoperative Radiotherapy after Resection
por: Herskind, Carsten, et al.
Publicado: (2017)

Preclinical investigations of the efficacy of the glutaminase inhibitor CB-839 alone and in combinations in chronic lymphocytic leukemia
por: Timofeeva, Natalia, et al.
Publicado: (2023)

Challenges of Using High-Dose Fractionation Radiotherapy in Combination Therapy
por: Yang, Ying-Chieh, et al.
Publicado: (2016)

Phytoradiotherapy: An Integrative Approach to Cancer Treatment by Combining Radiotherapy With Phytomedicines
por: Alfonzetti, Tyler, et al.
Publicado: (2021)

Confocal laser imaging in neurosurgery: A comprehensive review of sodium fluorescein-based CONVIVO preclinical and clinical applications
por: Restelli, Francesco, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_32k2v4mdc5l23r9ihr8q761vs2