Cargando…

The P2X7 Receptor is an Important Regulator of Extracellular ATP Levels

Controlled ATP release has been demonstrated from many neuronal and non-neuronal cell types. Once released, extracellular ATP acts on cells in a paracrine manner via purinergic receptors. Considerable evidence now suggests that extracellular nucleotides, signaling via P2 receptors, play important ro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brandao-Burch, Andrea, Key, Michelle L., Patel, Jessal J., Arnett, Timothy R., Orriss, Isabel R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355863/ https://www.ncbi.nlm.nih.gov/pubmed/22654865 http://dx.doi.org/10.3389/fendo.2012.00041

Ejemplares similares

Extracellular ATP Released by Osteoblasts Is A Key Local Inhibitor of Bone Mineralisation
por: Orriss, Isabel R., et al.
Publicado: (2013)

Modulation of osteoblast differentiation and function by the P2X4 receptor
por: Orriss, Isabel R., et al.
Publicado: (2022)

Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts
por: Patel, Jessal J., et al.
Publicado: (2019)

Acidosis Is a key regulator of osteoblast ecto‐nucleotidase pyrophosphatase/phosphodiesterase 1 (NPP1) expression and activity
por: Orriss, Isabel R., et al.
Publicado: (2015)

Structural basis for the functional properties of the P2X7 receptor for extracellular ATP
por: Jiang, Lin-Hua, et al.
Publicado: (2021)

Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation
por: Orriss, Isabel R., et al.
Publicado: (2016)

The P2X7 receptor modulates immune cells infiltration, ectonucleotidases expression and extracellular ATP levels in the tumor microenvironment
por: De Marchi, Elena, et al.
Publicado: (2019)

P2X7 Receptor in the Management of Energy Homeostasis: Implications for Obesity, Dyslipidemia, and Insulin Resistance
por: Coccurello, Roberto, et al.
Publicado: (2020)

Optimisation of the differing conditions required for bone formation in vitro by primary osteoblasts from mice and rats
por: ORRISS, ISABEL R., et al.
Publicado: (2014)

Quantitative Ubiquitinomics Revealed Abnormal Ubiquitinated ATP7A Involved in Down-Regulation of ACTH in Silent Corticotroph Adenomas
por: Zhao, Sida, et al.
Publicado: (2022)

Extracellular Nucleotides Regulate Arterial Calcification by Activating Both Independent and Dependent Purinergic Receptor Signaling Pathways
por: Opdebeeck, Britt, et al.
Publicado: (2020)

Extracellular Domain N-Glycosylation Controls Human Thrombopoietin Receptor Cell Surface Levels
por: Albu, Roxana I., et al.
Publicado: (2011)

Extracellular ATP and the P2X(7 )receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis
por: Gandelman, Mandi, et al.
Publicado: (2010)

Extracellular ATP does not induce P2X7 receptor-dependent responses in cultured renal- and liver-derived swine macrophages
por: Takenouchi, Takato, et al.
Publicado: (2014)

Extracellular ATP is a danger signal activating P2X7 receptor in a LPS mediated inflammation (ARDS/ALI)
por: Cicko, Sanja, et al.
Publicado: (2018)

Extracellular ATP and P(2)X(7) receptor exert context-specific immunogenic effects after immunogenic cancer cell death
por: Garg, A D, et al.
Publicado: (2016)

ATP Signaling Controlling Dyskinesia Through P2X7 Receptors
por: Fonteles, Analu A., et al.
Publicado: (2020)

Activation of P2X(7) Receptor by ATP Plays an Important Role in Regulating Inflammatory Responses during Acute Viral Infection
por: Lee, Benjamin H., et al.
Publicado: (2012)

The role of pregnane X receptor (PXR) in substance metabolism
por: Lv, Ye, et al.
Publicado: (2022)

Toll-Like Receptor-Mediated Activation of CD39 Internalization in BMDCs Leads to Extracellular ATP Accumulation and Facilitates P2X7 Receptor Activation
por: Zhao, Ronglan, et al.
Publicado: (2019)

Fibroblast growth factor 21 is expressed and secreted from skeletal muscle following electrical stimulation via extracellular ATP activation of the PI3K/Akt/mTOR signaling pathway
por: Arias-Calderón, Manuel, et al.
Publicado: (2023)

Animal diseases of public health importance.
por: Orriss, G D
Publicado: (1997)

Role of the Extracellular and Intracellular Loops of Follicle-Stimulating Hormone Receptor in Its Function
por: Banerjee, Antara A., et al.
Publicado: (2015)

Proteolytic Cleavage of the Extracellular Domain Affects Signaling of Parathyroid Hormone 1 Receptor
por: Klenk, Christoph, et al.
Publicado: (2022)

Extracellular ATP mediates inflammatory responses in colitis via P2 × 7 receptor signaling
por: Wan, Ping, et al.
Publicado: (2016)

Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors
por: Kurashima, Yosuke, et al.
Publicado: (2012)

P2X7-mediated ATP secretion is accompanied by depletion of cytosolic ATP
por: Johnsen, Bjarne, et al.
Publicado: (2019)

Retinoid X Receptors Intersect the Molecular Clockwork in the Regulation of Liver Metabolism
por: De Cosmo, Salvatore, et al.
Publicado: (2017)

P2X(7) Receptor and Extracellular Vesicle Release
por: Golia, Maria Teresa, et al.
Publicado: (2023)

Allosteric modulation of GABA(A) receptors by extracellular ATP
por: Liu, Jun, et al.
Publicado: (2014)

Strontium potently inhibits mineralisation in bone-forming primary rat osteoblast cultures and reduces numbers of osteoclasts in mouse marrow cultures
por: Wornham, D. P., et al.
Publicado: (2014)

Disrupted Lipid Metabolism in Multiple Sclerosis: A Role for Liver X Receptors?
por: Pineda-Torra, Inés, et al.
Publicado: (2021)

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity
por: Gannon, Anne-Louise, et al.
Publicado: (2021)

Molecular interplay between ecdysone receptor and retinoid X receptor in regulating the molting of the Chinese mitten crab, Eriocheir sinensis
por: Chen, Xiaowen, et al.
Publicado: (2023)

Differences in Signal Activation by LH and hCG are Mediated by the LH/CG Receptor’s Extracellular Hinge Region
por: Grzesik, Paul, et al.
Publicado: (2015)

Import of extracellular ATP in yeast and man modulates AMPK and TORC1 signalling
por: Forte, Gabriella M., et al.
Publicado: (2019)

Mineralisation of collagen rich soft tissues and osteocyte lacunae in Enpp1(−/−) mice
por: Hajjawi, Mark O.R., et al.
Publicado: (2014)

Importance of the Sequence-Directed DNA Shape for Specific Binding Site Recognition by the Estrogen-Related Receptor
por: Mohideen-Abdul, Kareem, et al.
Publicado: (2017)

Somatostatin Receptors and Analogs in Pheochromocytoma and Paraganglioma: Old Players in a New Precision Medicine World
por: Patel, Mayank, et al.
Publicado: (2021)

P2X7 Receptors Trigger ATP Exocytosis and Modify Secretory Vesicle Dynamics in Neuroblastoma Cells
por: Gutiérrez-Martín, Yolanda, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_3bcmsqam5ooj6frjboeuof3n35