Evaluation of Activity and Combination Strategies with the Microtubule-Targeting Drug Sagopilone in Breast Cancer Cell Lines

Sagopilone, a fully synthetic epothilone, is a microtubule-stabilizing agent optimized for high in vitro and in vivo activity against a broad range of tumor models, including those resistant to paclitaxel and other systemic treatments. Sagopilone development is accompanied by translational research...

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Detalles Bibliográficos
Autores principales: Eschenbrenner, Julia, Winsel, Sebastian, Hammer, Stefanie, Sommer, Anette, Mittelstaedt, Kevin, Drosch, Michael, Klar, Ulrich, Sachse, Christoph, Hannus, Michael, Seidel, Monika, Weiss, Bertram, Merz, Claudia, Siemeister, Gerhard, Hoffmann, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355879/
https://www.ncbi.nlm.nih.gov/pubmed/22649765
http://dx.doi.org/10.3389/fonc.2011.00044

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