Receptor Oligomerization in Family B1 of G-Protein-Coupled Receptors: Focus on BRET Investigations and the Link between GPCR Oligomerization and Binding Cooperativity

The superfamily of the seven transmembrane G-protein-coupled receptors (7TM/GPCRs) is the largest family of membrane-associated receptors. GPCRs are involved in the pathophysiology of numerous human diseases, and they constitute an estimated 30–40% of all drug targets. During the last two decades, G...

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Detalles Bibliográficos
Autores principales: Roed, Sarah Norklit, Orgaard, Anne, Jorgensen, Rasmus, Meyts, Pierre De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355942/
https://www.ncbi.nlm.nih.gov/pubmed/22649424
http://dx.doi.org/10.3389/fendo.2012.00062

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