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Glycogen Synthesis is Induced in Hypoxia by the Hypoxia-Inducible Factor and Promotes Cancer Cell Survival

The hypoxia-inducible factor 1 (HIF-1), in addition to genetic and epigenetic changes, is largely responsible for alterations in cell metabolism in hypoxic tumor cells. This transcription factor not only favors cell proliferation through the metabolic shift from oxidative phosphorylation to glycolys...

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Detalles Bibliográficos
Autores principales:	Pelletier, Joffrey, Bellot, Grégory, Gounon, Pierre, Lacas-Gervais, Sandra, Pouysségur, Jacques, Mazure, Nathalie M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355943/ https://www.ncbi.nlm.nih.gov/pubmed/22649778 http://dx.doi.org/10.3389/fonc.2012.00018

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