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Phase I Study of Celecoxib with Concurrent Irinotecan, Cisplatin, and Radiation Therapy for Patients with Unresectable Locally Advanced Non-Small Cell Lung Cancer

Purpose: Preclinical findings suggest that adding targeted therapies to combination radiation-chemotherapy can enhance treatment efficacy; however, this approach may enhance normal tissue toxicity. We investigated the maximum tolerated dose, dose-limiting toxicities, and response rate when the selec...

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Detalles Bibliográficos
Autores principales: Komaki, Ritsuko, Wei, Xiong, Allen, Pamela K., Liao, Zhongxing, Milas, Luka, Cox, James D., O’Reilly, Michael S., Chang, Joe Y., McAleer, Mary Frances, Jeter, Melenda, Blumenschein, George R., Kies, Merrill S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355954/
https://www.ncbi.nlm.nih.gov/pubmed/22649768
http://dx.doi.org/10.3389/fonc.2011.00052