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Different Approaches in Radiation Therapy of Craniopharyngioma

Radiation therapy is a cornerstone in the therapeutic management of craniopharyngioma. The close proximity to neighboring eloquent structures pose a particular challenge to radiation therapy. Modern treatment technologies including fractionated 3-D conformal radiotherapy, intensity modulated radiati...

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Autor principal: Kortmann, Rolf-Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356005/
https://www.ncbi.nlm.nih.gov/pubmed/22654836
http://dx.doi.org/10.3389/fendo.2011.00100
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author Kortmann, Rolf-Dieter
author_facet Kortmann, Rolf-Dieter
author_sort Kortmann, Rolf-Dieter
collection PubMed
description Radiation therapy is a cornerstone in the therapeutic management of craniopharyngioma. The close proximity to neighboring eloquent structures pose a particular challenge to radiation therapy. Modern treatment technologies including fractionated 3-D conformal radiotherapy, intensity modulated radiation therapy, and recently proton therapy are able to precisely cover the target while preserving surrounding tissue, Tumor controls between 80 and in access of 90% can be achieved. Alternative treatments consisting of radiosurgery, intracavitary application of isotopes, and brachytherapy also offer an acceptable tumor control and might be given in selected cases. More research is needed to establish the role of each treatment modality.
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spelling pubmed-33560052012-05-31 Different Approaches in Radiation Therapy of Craniopharyngioma Kortmann, Rolf-Dieter Front Endocrinol (Lausanne) Endocrinology Radiation therapy is a cornerstone in the therapeutic management of craniopharyngioma. The close proximity to neighboring eloquent structures pose a particular challenge to radiation therapy. Modern treatment technologies including fractionated 3-D conformal radiotherapy, intensity modulated radiation therapy, and recently proton therapy are able to precisely cover the target while preserving surrounding tissue, Tumor controls between 80 and in access of 90% can be achieved. Alternative treatments consisting of radiosurgery, intracavitary application of isotopes, and brachytherapy also offer an acceptable tumor control and might be given in selected cases. More research is needed to establish the role of each treatment modality. Frontiers Research Foundation 2011-12-20 /pmc/articles/PMC3356005/ /pubmed/22654836 http://dx.doi.org/10.3389/fendo.2011.00100 Text en Copyright © 2011 Kortmann. http://www.frontiersin.org/licenseagreement This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited.
spellingShingle Endocrinology
Kortmann, Rolf-Dieter
Different Approaches in Radiation Therapy of Craniopharyngioma
title Different Approaches in Radiation Therapy of Craniopharyngioma
title_full Different Approaches in Radiation Therapy of Craniopharyngioma
title_fullStr Different Approaches in Radiation Therapy of Craniopharyngioma
title_full_unstemmed Different Approaches in Radiation Therapy of Craniopharyngioma
title_short Different Approaches in Radiation Therapy of Craniopharyngioma
title_sort different approaches in radiation therapy of craniopharyngioma
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356005/
https://www.ncbi.nlm.nih.gov/pubmed/22654836
http://dx.doi.org/10.3389/fendo.2011.00100
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