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The Insulin Receptor: A New Target for Cancer Therapy

A large body of evidences have shown that both the IGF-I receptor (IGF-IR) and the insulin receptor (IR) play a role in cancer development and progression. In particular, IR overactivation by IGF-II is common in cancer cells, especially in dedifferentiated/stem-like cells. In spite of these findings...

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Detalles Bibliográficos
Autores principales:	Malaguarnera, Roberta, Belfiore, Antonino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2011
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356071/ https://www.ncbi.nlm.nih.gov/pubmed/22654833 http://dx.doi.org/10.3389/fendo.2011.00093

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