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Effects of a Fluorescent Myosin Light Chain Phosphatase Inhibitor on Prostate Cancer Cells
Myosin light chain phosphatase (MLCP) is an enzyme important to regulation of cell cycle and motility that is shown to be upregulated in aggressive prostate cancer cells and tissue. We developed a fluorescent small molecule inhibitor of MLCP using structure based design in recombinant protein phosph...
Autores principales: | Grindrod, Scott, Suy, Simeng, Fallen, Shannon, Eto, Masumi, Toretsky, Jeffrey, Brown, Milton L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356144/ https://www.ncbi.nlm.nih.gov/pubmed/22655237 http://dx.doi.org/10.3389/fonc.2011.00027 |
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