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Structure-dependent immunostimulatory effect of CpG oligodeoxynucleotides and their delivery system
Unmethylated cytosine-phosphate-guanosine (CpG) oligodeoxynucleotides (ODNs) are recognized by Toll-like receptor 9 (TLR9) found in antigen-presenting cells and B cells and can activate the immune system. Using CpG ODNs as an adjuvant has been found to be effective for treating infectious diseases,...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356174/ https://www.ncbi.nlm.nih.gov/pubmed/22619554 http://dx.doi.org/10.2147/IJN.S30197 |