A novel polyethyleneimine-coated adeno-associated virus-like particle formulation for efficient siRNA delivery in breast cancer therapy: preparation and in vitro analysis

BACKGROUND: Systemic delivery of small interfering RNA (siRNA) is limited by its poor stability and limited cell-penetrating properties. To overcome these limitations, we designed an efficient siRNA delivery system using polyethyleneimine-coated virus-like particles derived from adeno-associated vir...

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Detalles Bibliográficos
Autores principales: Shao, Wei, Paul, Arghya, Abbasi, Sana, Chahal, Parminder S, Mena, Jimmy A, Montes, Johnny, Kamen, Amine, Prakash, Satya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356177/
https://www.ncbi.nlm.nih.gov/pubmed/22619514
http://dx.doi.org/10.2147/IJN.S26891

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