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Self-assembled mPEG–PCL-g–PEI micelles for simultaneous codelivery of chemotherapeutic drugs and DNA: synthesis and characterization in vitro

BACKGROUND: In this paper, a series of amphiphilic triblock copolymers based on polyethylene glycol–poly ɛ-caprolactone–polyethylenimine (mPEG–PCL-g–PEI) were successfully synthesized, and their application for codelivery of chemotherapeutic drugs and DNA simultaneously was investigated. METHODS AND...

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Detalles Bibliográficos
Autores principales: Shi, Shuai, Zhu, Xuechen, Guo, QingFa, Wang, Yingjing, Zuo, Tao, Luo, Feng, Qian, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356179/
https://www.ncbi.nlm.nih.gov/pubmed/22619525
http://dx.doi.org/10.2147/IJN.S28932