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Preclinical evaluation of injectable sirolimus formulated with polymeric nanoparticle for cancer therapy
Nanoparticles are useful delivery vehicles for promising drug candidates that face obstacles for clinical applicability. Sirolimus, an inhibitor of mammalian target of rapamycin has gained attention for targeted anticancer therapy, but its clinical application has been limited by its poor solubility...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356221/ https://www.ncbi.nlm.nih.gov/pubmed/22619555 http://dx.doi.org/10.2147/IJN.S29480 |