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Preclinical evaluation of injectable sirolimus formulated with polymeric nanoparticle for cancer therapy

Nanoparticles are useful delivery vehicles for promising drug candidates that face obstacles for clinical applicability. Sirolimus, an inhibitor of mammalian target of rapamycin has gained attention for targeted anticancer therapy, but its clinical application has been limited by its poor solubility...

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Detalles Bibliográficos
Autores principales: Woo, Ha Na, Chung, Hye Kyung, Ju, Eun Jin, Jung, Joohee, Kang, Hye-Won, Lee, Sa-Won, Seo, Min-Hyo, Lee, Jin Seong, Lee, Jung Shin, Park, Heon Joo, Song, Si Yeol, Jeong, Seong-Yun, Choi, Eun Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356221/
https://www.ncbi.nlm.nih.gov/pubmed/22619555
http://dx.doi.org/10.2147/IJN.S29480

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