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Targeting Aquaporin Function: Potent Inhibition of Aquaglyceroporin-3 by a Gold-Based Compound
Aquaporins (AQPs) are membrane channels that conduct water and small solutes such as glycerol and are involved in many physiological functions. Aquaporin-based modulator drugs are predicted to be of broad potential utility in the treatment of several diseases. Until today few AQP inhibitors have bee...
Autores principales: | Martins, Ana Paula, Marrone, Alessandro, Ciancetta, Antonella, Galán Cobo, Ana, Echevarría, Miriam, Moura, Teresa F., Re, Nazzareno, Casini, Angela, Soveral, Graça |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356263/ https://www.ncbi.nlm.nih.gov/pubmed/22624030 http://dx.doi.org/10.1371/journal.pone.0037435 |
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