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Structural Dynamics of HIV-1 Envelope Gp120 Outer Domain with V3 Loop
BACKGROUND: The net charge of the hypervariable V3 loop on the HIV-1 envelope gp120 outer domain plays a key role in modulating viral phenotype. However, the molecular mechanisms underlying the modulation remain poorly understood. METHODOLOGY/PRINCIPAL FINDINGS: By combining computational and experi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356331/ https://www.ncbi.nlm.nih.gov/pubmed/22624045 http://dx.doi.org/10.1371/journal.pone.0037530 |