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Erythroid Promoter Confines FGF2 Expression to the Marrow after Hematopoietic Stem Cell Gene Therapy and Leads to Enhanced Endosteal Bone Formation

Fibroblast growth factor-2 (FGF2) has been demonstrated to be a promising osteogenic factor for treating osteoporosis. Our earlier study shows that transplantation of mouse Sca-1(+) hematopoietic stem/progenitor cells that are engineered to express a modified FGF2 leads to considerable endosteal/tra...

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Detalles Bibliográficos
Autores principales:	Meng, Xianmei, Baylink, David J., Sheng, Matilda, Wang, Hongjie, Gridley, Daila S., Lau, K.-H. William, Zhang, Xiao-Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356341/ https://www.ncbi.nlm.nih.gov/pubmed/22629419 http://dx.doi.org/10.1371/journal.pone.0037569

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