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α-Thalassemia Impairs the Cytoadherence of Plasmodium falciparum-Infected Erythrocytes
BACKGROUND: α-thalassemia results from decreased production of α-globin chains that make up part of hemoglobin tetramers (Hb; α(2)β(2)) and affects up to 50% of individuals in some regions of sub-Saharan Africa. Heterozygous (−α/αα) and homozygous (−α/−α) genotypes are associated with reduced risk o...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356384/ https://www.ncbi.nlm.nih.gov/pubmed/22623996 http://dx.doi.org/10.1371/journal.pone.0037214 |